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The Scientific Advisory Board: "We hope to see more data about the subgroups"

We were interested to know what our Scientific Advisory Board think about the research currently underway at Lund University Diabetes Centre (LUDC), and invited Flemming Pociot and Søren Brunak from the board to the LUDC retreat in Helsingborg recently. They spent their time at the retreat listening to presentations and getting updates, and were able to provide valuable feedback. A presentation ab

https://www.ludc.lu.se/article/scientific-advisory-board-we-hope-see-more-data-about-subgroups - 2025-10-01

Gut microbiome research indicates new bacteria and metformin associations

A large-scale faeces and blood sample study indicates strong associations between gut bacteria and metabolites in the blood. Among other findings, the research team behind the study has identified new associations between a common type 2 diabetes drug and the gut microbiome. The study was led by researchers at Uppsala University and Lund University. The role of the gut microbiome in disease and he

https://www.ludc.lu.se/article/gut-microbiome-research-indicates-new-bacteria-and-metformin-associations - 2025-10-01

Diabetes researcher Helena Elding Larsson wants to prevent type 1 diabetes from developing

Since Helena Elding Larsson began her career as a diabetes researcher and paediatrician, she has seen many improvements in the care of patients with diabetes. Her own research focuses on the prevention of the development of type 1 diabetes. Helena Elding Larsson is this year’s recipient of the Medeon stipend, and she will be speaking at the World Diabetes Day Skåne event, in Malmö on November 12th

https://www.ludc.lu.se/article/diabetes-researcher-helena-elding-larsson-wants-prevent-type-1-diabetes-developing - 2025-10-01

Several diabetes researchers at LUDC receive grants from the Swedish Research Council

Six researchers at Lund University Diabetes Centre (LUDC) were recently awarded grants within medicine and health by the Swedish Research Council (Vetenskapsrådet). The six researchers are members of the strategic research area Excellence of diabetes research in Sweden (EXODIAB) at Lund University. Daniel Agardh, adjunct professor in pediatrics and research group leader in celiac disease and diabe

https://www.ludc.lu.se/article/several-diabetes-researchers-ludc-receive-grants-swedish-research-council - 2025-10-01

Learning more about the endocrine system could lead to fewer cases of type 2 diabetes and obesity

How much water do we need to drink to stay healthy? How do different diets affect our metabolism? Studies of various hormones in the body are providing diabetes researchers with new answers to these questions. The goal is to develop individualized treatments and dietary recommendations that could lower the risk of developing obesity and diseases such as type 2 diabetes. The endocrine system and th

https://www.ludc.lu.se/article/learning-more-about-endocrine-system-could-lead-fewer-cases-type-2-diabetes-and-obesity - 2025-10-01

ERC grant for research on diabetes

Professor Charlotte Ling at Lund University Diabetes Centre (LUDC) has been awarded a Proof of Concept Grant by the European Research Council, ERC, for the further development of her successful research on epigenetic biomarkers. The innovation-driven research project will investigate biomarkers for predicting who benefits from metformin in the treatment of type 2 diabetes. In her research, Charlot

https://www.ludc.lu.se/article/erc-grant-research-diabetes - 2025-10-01

Diabetes researcher Tove Fall is the recipient of the Leif C. Groop award 2023

Tove Fall became a familiar face during the Covid-19 pandemic when she was often seen in Swedish media talking about the spread and progression of the disease in Sweden. She is also an outstanding diabetes researcher who uses large quantities of data to gain a better understanding of the development of diabetes. Tove Fall is now awarded the Leif C. Groop award for outstanding diabetes research for

https://www.ludc.lu.se/article/diabetes-researcher-tove-fall-recipient-leif-c-groop-award-2023 - 2025-10-01

PAX5 – a gene strongly associated with impaired insulin secretion in type 2 diabetes

Researchers have identified 395 genes that are differently expressed in people with type 2 diabetes. One of the genes proved to be very strongly associated with impaired insulin secretion. Now, researchers want to investigate if it is possible to use the genetic CRISPR/Cas9 scissors to correct the gene’s activity. The research team’s scientific paper was published in the Journal of Clinical Invest

https://www.ludc.lu.se/article/pax5-gene-strongly-associated-impaired-insulin-secretion-type-2-diabetes - 2025-10-01

A genetic-driven approach defining two obesity profiles that convey highly concordant and discordant diabetogenic effects

A team of researchers led by Daniel E. Coral and Paul W. Franks at LUDC have used human genetics to do a phenome-wide analysis of the degree of genetic dissimilarity between obesity and type 2 diabetes. Together with colleagues from Dundee and Oxford universities in the UK and the Vanderbilt Genetics Institute in the US, the team recently published their findings in the journal Nature Metabolism.

https://www.ludc.lu.se/article/genetic-driven-approach-defining-two-obesity-profiles-convey-highly-concordant-and-discordant - 2025-10-01

Swedish research about different forms of type 2 diabetes is relevant for Indian people

Researchers at Lund University have previously shown that type 1 diabetes and type 2 diabetes can be divided into five subgroups, and that there are genetic differences between the four subgroups relating to type 2 diabetes. A research collaboration between Sweden and India now highlights similarities and differences between patient groups in India and Europe. The knowledge can be used to improve

https://www.ludc.lu.se/article/swedish-research-about-different-forms-type-2-diabetes-relevant-indian-people - 2025-10-01

Epigenetics and genetics help illustrate how diabetes care can be individualised

Precision medicine aims to deliver the right treatment to the right person at the right time. What does this mean for people with type 2 diabetes? Some of the research at Lund University Diabetes Centre (LUDC) focuses on the progression of type 2 diabetes to help develop more targeted treatments. Epigenetics can become a useful tool when diabetes care is tailored to the individual. People with typ

https://www.ludc.lu.se/article/epigenetics-and-genetics-help-illustrate-how-diabetes-care-can-be-individualised - 2025-10-01

New discoveries about where atherosclerotic plaques rupture can lead to preventive treatments

A common cause of myocardial infarction and stroke is the rupture of atherosclerotic plaques. The exact location of plaque ruptures has previously been unknown, but now researchers at Lund University have mapped this. The research team has also identified an enzyme, a marker, that they hope will help predict who is at risk of having a myocardial infarction or a stroke due to a ruptured atheroscler

https://www.ludc.lu.se/article/new-discoveries-about-where-atherosclerotic-plaques-rupture-can-lead-preventive-treatments - 2025-10-01

Type 2 diabetes researchers receive support from the Hjelt Diabetes Foundation

Every year, the Bo and Kerstin Hjelt Diabetes Foundation awards three diabetes researchers at Lund University Diabetes Centre (LUDC) each a project grant of 47,500 euro. One of the researchers awarded a grant this year studies atherosclerotic plaques in patients with type 2 diabetes. These patients are more likely to develop cardiovascular disease due to plaque rupture compared to people without t

https://www.ludc.lu.se/article/type-2-diabetes-researchers-receive-support-hjelt-diabetes-foundation - 2025-10-01

Gut and mouth bacteria give researchers new clues about atherosclerosis

What is the link between atherosclerosis and gut and mouth bacteria? Researchers behind a large new study have found several new connections. In the long term, this knowledge can benefit people with type 2 diabetes, a group with an increased risk of developing atherosclerosis. In atherosclerosis, fat and calcium have accumulated in the artery walls over time, forming so called atherosclerotic plaq

https://www.ludc.lu.se/article/gut-and-mouth-bacteria-give-researchers-new-clues-about-atherosclerosis - 2025-10-01

Positive metabolic effects of gastric bypass disappear quickly

A new study from Lund University in Sweden raises questions about the efficacy of bariatric operations involving gastric bypass. The results show that the biggest metabolic changes happened directly after surgery. Just a year after the operation, the concentration of metabolites and fats had returned to almost the same levels as before the procedure.  Previous research has shown that the majority

https://www.ludc.lu.se/article/positive-metabolic-effects-gastric-bypass-disappear-quickly - 2025-10-01

Blåmesar trögare än talgoxar

Blåmesar är inte lika läraktiga som talgoxar. Men de nyfikna mesarna presterar ändå bättre än många andra fågelarter i kognitiva tester. Det visar en ny impulsstudie från Lunds universitet. Självkontroll är svårt för djur och brukar därför användas som jämförande mått när man vill undersöka allmän kognitiv förmåga hos olika arter. Det vanligaste verktyget är ”det transparenta cylindertestet”. Expe

https://www.biologi.lu.se/artikel/blamesar-trogare-talgoxar - 2025-10-01

Bins utsatthet för bekämpningsmedel är art- och landskapsberoende

Nu finns det bevis på att bins exponering för bekämpningsmedel beror på deras samspel med miljön. Enligt forskare från Lunds universitet och Sveriges Lantbruksuniversitet, ökar binas bekämpningsmedelsrelaterade risker ju mer jordbruksmark som omger dem. Men detta gäller bara för det solitära biet och humlan, arter som söker föda över mindre ytor än honungsbiet. Denna upptäckt stöder de semi-naturl

https://www.biologi.lu.se/artikel/bins-utsatthet-bekampningsmedel-ar-art-och-landskapsberoende - 2025-10-01

Flyttfåglar rastar för att boosta immunförsvaret

Tränar du för mycket och inte vilar tillräckligt är det dåligt för hälsan. Nu visar en studie från Lunds universitet att samma sak gäller för flyttfåglar. De behöver ta rast inte bara för att få ny energi utan även för att boosta immunförsvaret. Efter en period av ansträngande fysisk aktivitet behöver ryggradsdjur, inklusive människor, vanligtvis en period av återhämtning. Förutom det uppenbara –

https://www.biologi.lu.se/artikel/flyttfaglar-rastar-att-boosta-immunforsvaret - 2025-10-01

Fågelmatning gör småfåglar friskare

Frön och talgbollar genererar inte bara mätta småfågelmagar. Ny forskning från Lunds universitet visar att matning under vinterhalvåret får fåglarna att bli friskare eftersom de inte behöver lägga lika mycket energi på att bekämpa infektioner. En liten förändring i kroppstemperatur kan vara direkt dödlig för människan. Småfåglar, däremot, sänker sin nattliga kroppstemperatur med flera grader under

https://www.biologi.lu.se/artikel/fagelmatning-gor-smafaglar-friskare - 2025-10-01